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Benefits & Disadvantages of Tianeptine Hemisulfate Monohydrate
Jul 25, 2018

Benefits: Tianeptine Sulphate, also known as Tianeptine Hemisulfate Monohydrate, is a Tricyclic

Anti-depressant (TCA) and as this might suggest, its predominant use is for the treatment of depression. Tianeptine Sulphate is superior for three fundamental reasons:




Firstly, Tianeptine Sodium is notoriously unstable, reacting to both atmospheric moisture and light. Tianeptine sulphate on the other hand is non-hygroscopic, meaning that it is doesn’t absorb the water from the air, and doesn’t clump.

Secondly, Tianeptine sodium is not soluble, which wouldn’t be so bad if not for the fact that it tastes awful and when using it you may have to dose up to three times per day. Tianeptine sulphate on the other hand is soluble, meaning that you can simply mix it with water for a quick and easy drink.


Thirdly, and most importantly, Tianeptine Sodium is only effective for a relatively short duration, meaning that it has to be frequently dosed, sometimes up to three or four times a day according to anecdotal reviews. From a medical perspective this can lead to a decreased adherence to dosing regimen and reduced effectiveness as a result. Tianeptine Sulphate, however, is absorbed by the body at a much slower rate, taking longer to reach its peak effect and extending its duration within the body, meaning that less frequent dosing is required; effectively solving one of the main problems of the Sodium form.

Disadvantages: Please kindly note that it has not been approved, nor have these statements been evaluated, by the FDA.

There are no official precautions to be observed for Tianeptine Sulfate. Its most common side effects are headaches, constipation, insomnia/nightmares, dry mouth and dizziness